Advanced Synthesis & Catalysis期刊最新论文, 化学 • 材料...

来自 : www.x-mol.com/paper/journal... 发布时间：2021-03-25

Employing silver/rhodium relay catalysis strategy, an intramolecular electrophilic cyclization and C‐H activation followed by cascade hydrogenation and reductive amination has been developed. The acylmethylated isoquinoline derivatives could be afforded with broad substrate scope in 23‐88% yields, which could be further transformed to the core skeleton of hexahydrodibenzo[a,g]quinolizine as drug‐candidates

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